Version 5.4
Homo sapiens Protein: SNX22
Summary
InnateDB Protein IDBP-16340.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNX22
Protein Name sorting nexin 22
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000323435
InnateDB Gene IDBG-16336 (SNX22)
Protein Structure
UniProt Annotation
Function May be involved in several stages of intracellular trafficking (By similarity). Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)). {ECO:0000250}.
Subcellular Localization Cytoplasmic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 8 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0015031 protein transport
Cellular Component
GO:0030659 cytoplasmic vesicle membrane
Protein Structure and Domains
PDB ID
InterPro IPR001683 Phox homologous domain
PFAM PF00787
PRINTS
PIRSF
SMART SM00312
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96L94
PhosphoSite PhosphoSite-Q96L94
TrEMBL Q8WUS9
UniProt Splice Variant
Entrez Gene 79856
UniGene Hs.708268
RefSeq NP_079074
HUGO HGNC:16315
OMIM
CCDS CCDS10190
HPRD 15412
IMGT
EMBL AC100840 AK024014 AY044653 BC019655 CH471082
GenPept AAH19655 AAK98767 BAB14776 EAW77667 EAW77668

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca