InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cd226

Summary

InnateDB Protein

IDBP-163480.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cd226

Protein Name

CD226 antigen

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000043551

InnateDB Gene

IDBG-163478 (Cd226)

Protein Structure

UniProt Annotation

Function

Receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. {ECO:0000250}.

Subcellular Localization

Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005178	integrin binding
GO:0005515	protein binding
GO:0019901	protein kinase binding
GO:0050839	cell adhesion molecule binding

Biological Process

GO:0001816	cytokine production
GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0002891	positive regulation of immunoglobulin mediated immune response
GO:0007155	cell adhesion
GO:0033005	positive regulation of mast cell activation
GO:0045954	positive regulation of natural killer cell mediated cytotoxicity
GO:0060369	positive regulation of Fc receptor mediated stimulatory signaling pathway