Mus musculus Protein: Dok6
Summary
InnateDB Protein IDBP-163585.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dok6
Protein Name docking protein 6
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000095103
InnateDB Gene IDBG-163583 (Dok6)
Protein Structure
UniProt Annotation
Function DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret- mediated neurite growth. May have a role in brain development and/or maintenance (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005158 insulin receptor binding
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:3639495
InterPro IPR001849 Pleckstrin homology domain
IPR002404 Insulin receptor substrate-1, PTB
PFAM PF00169
PF02174
PRINTS PR00628
PIRSF
SMART SM00233
SM00310
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2MHE5
PhosphoSite PhosphoSite-Q2MHE5
TrEMBL
UniProt Splice Variant
Entrez Gene 623279
UniGene Mm.447164
RefSeq NP_001034262
MGI ID
MGI Symbol Dok6
OMIM
CCDS CCDS37878
HPRD
IMGT
EMBL AB221044 BC138955 BC138957
GenPept AAI38956 AAI38958 BAE75920