Version 5.4
Mus musculus Protein: Tff2
Summary
InnateDB Protein IDBP-163788.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tff2
Protein Name trefoil factor 2 (spasmolytic protein 1)
Synonyms mSP; SP;
Species Mus musculus
Ensembl Protein ENSMUSP00000024826
InnateDB Gene IDBG-163786 (Tff2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0031723 CXCR4 chemokine receptor binding
Biological Process
GO:0008284 positive regulation of cell proliferation
GO:0019722 calcium-mediated signaling
GO:0030334 regulation of cell migration
GO:0043031 negative regulation of macrophage activation
GO:0050728 negative regulation of inflammatory response
GO:0060455 negative regulation of gastric acid secretion
GO:0070098 chemokine-mediated signaling pathway
GO:0070374 positive regulation of ERK1 and ERK2 cascade
Cellular Component
GO:0005615 extracellular space
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1306805
InterPro IPR000519 P-type trefoil
IPR017994 P-type trefoil, chordata
PFAM PF00088
PRINTS PR00680
PIRSF
SMART SM00018
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9QX97
UniProt Splice Variant
Entrez Gene 21785
UniGene Mm.1825
RefSeq NP_033389
MGI ID
MGI Symbol Tff2
OMIM
CCDS CCDS37545
HPRD
IMGT
EMBL AC167247 AJ271003 AK003093 BC050086 BC087889 CH466640
GenPept AAH50086 AAH87889 BAB22560 CAB65751 EDL40375

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca