Version 5.4
Mus musculus Protein: Rsph1
Summary
InnateDB Protein IDBP-164055.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rsph1
Protein Name radial spoke head 1 homolog (Chlamydomonas)
Synonyms MCA; Tsga2;
Species Mus musculus
Ensembl Protein ENSMUSP00000024832
InnateDB Gene IDBG-164053 (Rsph1)
Protein Structure
UniProt Annotation
Function The specific expression during male germ cell development and its characteristic localization suggest that it may play an important role in male meiosis. It is necessary for proper building of the axonemal central pair and radial spokes (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm. Chromosome. Cell projection, cilium {ECO:0000250}. Note=Cytoplasmic in late spermatocytes, secondary spermatocytes and round spermatids. Gathered around metaphase chromosomes during meiotic divisions.
Disease Associations
Tissue Specificity Germ cell specific. Specifically expressed in testis, and to a lower extent in ovary. Not expressed in somatic tissues.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007126 meiotic nuclear division
GO:0035082 axoneme assembly
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005829 cytosol
GO:0031514 motile cilium
Protein Structure and Domains
PDB ID MGI:1194909
InterPro IPR003409 MORN motif
PFAM PF02493
PRINTS
PIRSF
SMART SM00698
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8VIG3
PhosphoSite PhosphoSite-Q8VIG3
TrEMBL Q3YEA4
UniProt Splice Variant
Entrez Gene 22092
UniGene Mm.12743
RefSeq NP_079566
MGI ID
MGI Symbol Rsph1
OMIM
CCDS CCDS28604
HPRD
IMGT
EMBL AB006535 AK005739 BC049584 CH466640 DQ141550 DQ141551
GenPept AAH49584 AAZ75688 AAZ75689 BAB24214 BAB83693 EDL40363

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca