Mus musculus Protein: Pknox1
Summary
InnateDB Protein IDBP-164530.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pknox1
Protein Name Pbx/knotted 1 homeobox
Synonyms D17Wsu76e; PREP1;
Species Mus musculus
Ensembl Protein ENSMUSP00000094966
InnateDB Gene IDBG-164528 (Pknox1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 11 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003705 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0001525 angiogenesis
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0030097 hemopoiesis
GO:0030217 T cell differentiation
GO:0030218 erythrocyte differentiation
GO:0043010 camera-type eye development
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1201409
InterPro IPR001356 Homeobox domain
IPR008422 Homeobox KN domain
IPR009057 Homeodomain-like
PFAM PF00046
PF05920
PRINTS
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O70477
PhosphoSite PhosphoSite-O70477
TrEMBL
UniProt Splice Variant
Entrez Gene 18771
UniGene Mm.401586
RefSeq NP_057879
MGI ID
MGI Symbol Pknox1
OMIM
CCDS CCDS28608
HPRD
IMGT
EMBL AF061270 AK131788 AK134000 BC052701
GenPept AAC15990 AAH52701 BAE20805 BAE21975