InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pcyox1

Summary

InnateDB Protein

IDBP-164589.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pcyox1

Protein Name

prenylcysteine oxidase 1

Synonyms

1200015P13Rik; AI115532; AI448340; PCL1; Pcly;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000032065

InnateDB Gene

IDBG-164587 (Pcyox1)

Protein Structure

UniProt Annotation

Function

Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine (By similarity). {ECO:0000250}.

Subcellular Localization

Lysosome {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	14 [view]
Protein-Protein	14 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001735	prenylcysteine oxidase activity
GO:0008555	chloride-transporting ATPase activity
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor

Biological Process

GO:0006821	chloride transport
GO:0030327	prenylated protein catabolic process
GO:0030328	prenylcysteine catabolic process
GO:0055114	oxidation-reduction process
GO:1902476	chloride transmembrane transport