Mus musculus Protein: Rabgap1 | |||||||||
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Summary | |||||||||
InnateDB Protein | IDBP-165903.6 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | Rabgap1 | ||||||||
Protein Name | RAB GTPase activating protein 1 | ||||||||
Synonyms | |||||||||
Species | Mus musculus | ||||||||
Ensembl Protein | ENSMUSP00000061624 | ||||||||
InnateDB Gene | IDBG-165901 (Rabgap1) | ||||||||
Protein Structure | |||||||||
UniProt Annotation | |||||||||
Function | May act as a GTPase-activating protein of RAB6A. May play a role in microtubule nucleation by centrosome. May participate in a RAB6A-mediated pathway involved in the metaphase- anaphase transition (By similarity). {ECO:0000250UniProtKB:Q9Y3P9}. | ||||||||
Subcellular Localization | Cytoplasm, cytosol {ECO:0000250UniProtKB:Q9Y3P9}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250UniProtKB:Q9Y3P9}. Note=Predominantly cytosolic but also associated with the centrosome. {ECO:0000250UniProtKB:Q9Y3P9}. | ||||||||
Disease Associations | |||||||||
Tissue Specificity | |||||||||
Comments | |||||||||
Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||
PDB ID | MGI:2385139 | ||||||||
InterPro |
IPR000195
Rab-GTPase-TBC domain IPR006020 PTB/PI domain IPR022164 Kinesin-like |
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PFAM |
PF00566
PF00640 PF14719 PF12473 |
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PRINTS | |||||||||
PIRSF | |||||||||
SMART |
SM00164
SM00462 |
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TIGRFAMs | |||||||||
Post-translational Modifications | |||||||||
Modification | |||||||||
Cross-References | |||||||||
SwissProt | A2AWA9 | ||||||||
PhosphoSite | PhosphoSite-A2AWA9 | ||||||||
TrEMBL | B2RRC5 | ||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | 227800 | ||||||||
UniGene | Mm.438200 | ||||||||
RefSeq | NP_666233 | ||||||||
MGI ID | |||||||||
MGI Symbol | Rabgap1 | ||||||||
OMIM | |||||||||
CCDS | CCDS16002 | ||||||||
HPRD | |||||||||
IMGT | |||||||||
EMBL | AK031315 AK044346 AK051644 AK220489 AL953890 BC026862 BC031714 BC138337 CH466542 | ||||||||
GenPept | AAH26862 AAH31714 AAI38338 BAC27344 BAC31880 BAC34703 BAD90509 CAM20742 CAM20743 EDL08711 | ||||||||