Mus musculus Protein: Rabgap1
Summary
InnateDB Protein IDBP-165905.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rabgap1
Protein Name RAB GTPase activating protein 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000068835
InnateDB Gene IDBG-165901 (Rabgap1)
Protein Structure
UniProt Annotation
Function May act as a GTPase-activating protein of RAB6A. May play a role in microtubule nucleation by centrosome. May participate in a RAB6A-mediated pathway involved in the metaphase- anaphase transition (By similarity). {ECO:0000250UniProtKB:Q9Y3P9}.
Subcellular Localization Cytoplasm, cytosol {ECO:0000250UniProtKB:Q9Y3P9}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250UniProtKB:Q9Y3P9}. Note=Predominantly cytosolic but also associated with the centrosome. {ECO:0000250UniProtKB:Q9Y3P9}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005097 Rab GTPase activator activity
GO:0005515 protein binding
Biological Process
GO:0007049 cell cycle
GO:0008150 biological_process
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
Cellular Component
GO:0005575 cellular_component
GO:0005815 microtubule organizing center
GO:0005829 cytosol
Protein Structure and Domains
PDB ID MGI:2385139
InterPro IPR000195 Rab-GTPase-TBC domain
IPR006020 PTB/PI domain
IPR022164 Kinesin-like
PFAM PF00566
PF00640
PF14719
PF12473
PRINTS
PIRSF
SMART SM00164
SM00462
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A2AWA9
PhosphoSite PhosphoSite-A2AWA9
TrEMBL A2AWB0
UniProt Splice Variant
Entrez Gene 227800
UniGene Mm.438200
RefSeq NP_001029132
MGI ID
MGI Symbol Rabgap1
OMIM
CCDS CCDS16003
HPRD
IMGT
EMBL AK031315 AK044346 AK051644 AK220489 AL953890 BC026862 BC031714
GenPept AAH26862 AAH31714 BAC27344 BAC31880 BAC34703 BAD90509 CAM20742 CAM20743