InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Col6a2

Summary

InnateDB Protein

IDBP-165970.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Col6a2

Protein Name

collagen, type VI, alpha 2

Synonyms

Col6a-2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000001181

InnateDB Gene

IDBG-165968 (Col6a2)

Protein Structure

UniProt Annotation

Function

Collagen VI acts as a cell-binding protein.

Subcellular Localization

Secreted, extracellular space, extracellular matrix {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Recruited on membranes by CSPG4. {ECO:0000250}.

Disease Associations

Tissue Specificity

Highly expressed in adipose tissue, lung, adrenal glands and ovary. Lower levels in testis, tongue, skin, kidney, heart, intestine and spleen. No expression in skeletal muscle or liver.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0007155	cell adhesion
GO:0009749	response to glucose
GO:0070208	protein heterotrimerization

Cellular Component

GO:0005576	extracellular region
GO:0005578	proteinaceous extracellular matrix
GO:0005581	collagen trimer
GO:0005615	extracellular space
GO:0031012	extracellular matrix
GO:0042383	sarcolemma
GO:0043234	protein complex
GO:0070062	extracellular vesicular exosome