Version 5.4
Mus musculus Protein: Ubr7
Summary
InnateDB Protein IDBP-166076.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ubr7
Protein Name ubiquitin protein ligase E3 component n-recognin 7 (putative)
Synonyms 5730410I19Rik; AA589405; AW557761;
Species Mus musculus
Ensembl Protein ENSMUSP00000041247
InnateDB Gene IDBG-166074 (Ubr7)
Protein Structure
UniProt Annotation
Function E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0008270 zinc ion binding
GO:0016874 ligase activity
Biological Process
GO:0008150 biological_process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:1913872
InterPro IPR003126 Zinc finger, N-recognin
IPR011011 Zinc finger, FYVE/PHD-type
IPR013993 Zinc finger, N-recognin, metazoa
PFAM PF02207
PRINTS
PIRSF
SMART SM00396
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BU04
PhosphoSite PhosphoSite-Q8BU04
TrEMBL Q6PDS2
UniProt Splice Variant
Entrez Gene 66622
UniGene Mm.34261
RefSeq NP_079942
MGI ID
MGI Symbol Ubr7
OMIM
CCDS CCDS26124
HPRD
IMGT
EMBL AK088208 AK149989 AK155611 BC051678 BC058535 BC079531 BC094423 CH466549
GenPept AAH51678 AAH58535 AAH79531 AAH94423 BAC40212 BAE29217 BAE33345 EDL18852

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca