Homo sapiens Protein: RNF122
Summary
InnateDB Protein IDBP-16614.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNF122
Protein Name ring finger protein 122
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000256257
InnateDB Gene IDBG-16612 (RNF122)
Protein Structure
UniProt Annotation
Function May induce necrosis and apoptosis. May play a role in cell viability. {ECO:0000269PubMed:16751333}.
Subcellular Localization Golgi apparatus {ECO:0000269PubMed:16778963}. Endoplasmic reticulum {ECO:0000269PubMed:16778963}. Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Widely expressed in several tissues and cell lines. {ECO:0000269PubMed:16778963}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001841 Zinc finger, RING-type
IPR018957 Zinc finger, C3HC4 RING-type
PFAM PF13639
PF14634
PF00097
PRINTS
PIRSF
SMART SM00184
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H9V4
PhosphoSite PhosphoSite-Q9H9V4
TrEMBL
UniProt Splice Variant
Entrez Gene 79845
UniGene Hs.151237
RefSeq NP_079063
HUGO HGNC:21147
OMIM
CCDS CCDS6091
HPRD 11498
IMGT
EMBL AK022588 BC093884 BC101573
GenPept AAH93884 AAI01574 BAB14115