Mus musculus Protein: Rab39 | |||||||||||||||||
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Summary | |||||||||||||||||
InnateDB Protein | IDBP-166153.6 | ||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
Gene Symbol | Rab39 | ||||||||||||||||
Protein Name | RAB39, member RAS oncogene family | ||||||||||||||||
Synonyms | |||||||||||||||||
Species | Mus musculus | ||||||||||||||||
Ensembl Protein | ENSMUSP00000063804 | ||||||||||||||||
InnateDB Gene | IDBG-166151 (Rab39) | ||||||||||||||||
Protein Structure | |||||||||||||||||
UniProt Annotation | |||||||||||||||||
Function | Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in vesicular trafficking. Plays a role in the fusion of phagosomes with lysosomes (By similarity). {ECO:0000250}. | ||||||||||||||||
Subcellular Localization | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasmic vesicle, phagosome {ECO:0000250}. Cytoplasmic vesicle, phagosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Recruited to phagosomes containing S.aureus or Mycobacterium. {ECO:0000250}. | ||||||||||||||||
Disease Associations | |||||||||||||||||
Tissue Specificity | |||||||||||||||||
Comments | |||||||||||||||||
Interactions | |||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||||||||
PDB ID | MGI:2442855 | ||||||||||||||||
InterPro |
IPR001806
Small GTPase superfamily IPR002041 Ran GTPase IPR003578 Small GTPase superfamily, Rho type IPR003579 Small GTPase superfamily, Rab type IPR005225 Small GTP-binding protein domain IPR006689 Small GTPase superfamily, ARF/SAR type IPR006762 Gtr1/RagA G protein IPR013684 Mitochondrial Rho-like IPR020849 Small GTPase superfamily, Ras type IPR027417 P-loop containing nucleoside triphosphate hydrolase |
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PFAM |
PF00071
PF00025 PF04670 PF08477 |
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PRINTS |
PR00449
PR00627 PR00328 |
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PIRSF | |||||||||||||||||
SMART |
SM00176
SM00174 SM00175 SM00173 |
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TIGRFAMs | |||||||||||||||||
Post-translational Modifications | |||||||||||||||||
Modification | |||||||||||||||||
Cross-References | |||||||||||||||||
SwissProt | Q8BHD0 | ||||||||||||||||
PhosphoSite | PhosphoSite-Q8BHD0 | ||||||||||||||||
TrEMBL | Q0PD15 | ||||||||||||||||
UniProt Splice Variant | |||||||||||||||||
Entrez Gene | 270160 | ||||||||||||||||
UniGene | Mm.403787 | ||||||||||||||||
RefSeq | NP_780771 | ||||||||||||||||
MGI ID | |||||||||||||||||
MGI Symbol | Rab39 | ||||||||||||||||
OMIM | |||||||||||||||||
CCDS | CCDS23185 | ||||||||||||||||
HPRD | |||||||||||||||||
IMGT | |||||||||||||||||
EMBL | AB232635 AK049038 AK053487 BC049787 CH466522 | ||||||||||||||||
GenPept | AAH49787 BAC33522 BAC35399 BAF02897 EDL25801 | ||||||||||||||||