InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Trim41

Summary

InnateDB Protein

IDBP-166268.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Trim41

Protein Name

tripartite motif-containing 41

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000037055

InnateDB Gene

IDBG-166266 (Trim41)

Protein Structure

UniProt Annotation

Function

Functions as an E3 ligase that catalyzes the ubiquitin- mediated degradation of protein kinase C. {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.

Predicted by orthology
Total	24 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016874	ligase activity
GO:0046872	metal ion binding

Biological Process

GO:0008150	biological_process
GO:0016567	protein ubiquitination

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:2384814

InterPro

IPR000315 Zinc finger, B-box
IPR001841 Zinc finger, RING-type
IPR001870 B30.2/SPRY domain
IPR003877 SPla/RYanodine receptor SPRY
IPR003879 Butyrophylin-like
IPR006574 SPRY-associated
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR018355 SPla/RYanodine receptor subgroup
IPR018957 Zinc finger, C3HC4 RING-type
IPR022081 Domain of unknown function DUF3631

PFAM