Version 5.4
Mus musculus Protein: Gldn
Summary
InnateDB Protein IDBP-166465.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gldn
Protein Name gliomedin
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000056080
InnateDB Gene IDBG-166463 (Gldn)
Protein Structure
UniProt Annotation
Function Plays a role in the formation of the nodes of Ranvier along myelinated axons. Probable NRCAM and NFASC/neurofascin ligand which may provide a glial positional clue required for the proper molecular assembly of the nodes of Ranvier (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane; Single-pass type II membrane protein. Note=Localizes to the nodes of Ranvier. {ECO:0000250}.
Disease Associations
Tissue Specificity Widely expressed with higher expression in testis and skeletal muscle. {ECO:0000269PubMed:12642876}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0086080 protein binding involved in heterotypic cell-cell adhesion
Biological Process
GO:0032528 microvillus organization
GO:0034113 heterotypic cell-cell adhesion
GO:0045162 clustering of voltage-gated sodium channels
Cellular Component
GO:0005581 collagen trimer
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2388361
InterPro IPR003112 Olfactomedin-like
IPR008160 Collagen triple helix repeat
PFAM PF02191
PF01391
PRINTS
PIRSF
SMART SM00284
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BMF8
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 235379
UniGene Mm.123549
RefSeq NP_796324
MGI ID
MGI Symbol Gldn
OMIM
CCDS CCDS23189
HPRD
IMGT
EMBL AF548022 AK031523
GenPept AAO49510 BAC27432

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca