Version 5.4
Mus musculus Protein: Insl3
Summary
InnateDB Protein IDBP-166654.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Insl3
Protein Name insulin-like 3
Synonyms Rlf; Rlnl;
Species Mus musculus
Ensembl Protein ENSMUSP00000034261
InnateDB Gene IDBG-261182 (Insl3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001664 G-protein coupled receptor binding
GO:0002020 protease binding
GO:0005179 hormone activity
Biological Process
GO:0001556 oocyte maturation
GO:0001701 in utero embryonic development
GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0008284 positive regulation of cell proliferation
GO:0008285 negative regulation of cell proliferation
GO:0008584 male gonad development
GO:0030819 positive regulation of cAMP biosynthetic process
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID MGI:108427
InterPro IPR016179 Insulin-like
IPR022352 Insulin family
PFAM PF00049
PRINTS PR00276
PIRSF
SMART SM00078
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5RL10
UniProt Splice Variant
Entrez Gene 16336
UniGene
RefSeq NP_038592
MGI ID
MGI Symbol Insl3
OMIM
CCDS CCDS22404
HPRD
IMGT
EMBL AC162033 AK132857 BC049540 CH466569
GenPept AAH49540 BAE21395 EDL28953

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca