InnateDB Protein
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IDBP-167011.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Zfp422
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Protein Name
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zinc finger protein 422
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Synonyms
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2900028O21Rik; AU041373; KOX15; Krox-25-2; Krox-26; Krox25; Krox26; Znf22;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000084926
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InnateDB Gene
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IDBG-180841 (Zfp422)
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Protein Structure
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Function |
Binds DNA through the consensus sequence 5'-CAATG-3'. May be involved in transcriptional regulation and may play a role in tooth formation. {ECO:0000269PubMed:12952191, ECO:0000303PubMed:12489153}.
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Subcellular Localization |
Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Expressed predominantly in developing craniofacial bones and dental organs, and in molar tooth germs of postnatal animals. Also detected in embryonic heart, liver, thymus, kidney, brain, lung, muscle and calvaria. In the adult, highly expressed in lung, kidney, bone and incisors. {ECO:0000269PubMed:12489153, ECO:0000269PubMed:12952191, ECO:0000269PubMed:14706453}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
5
[view]
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Protein-Protein |
5
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1914505
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InterPro |
IPR007087
Zinc finger, C2H2
IPR015880
Zinc finger, C2H2-like
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PFAM |
PF00096
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PRINTS |
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PIRSF |
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SMART |
SM00355
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TIGRFAMs |
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Modification |
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SwissProt |
Q9ERU3
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PhosphoSite |
PhosphoSite-Q9ERU3
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
67255
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UniGene |
Mm.406226
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RefSeq |
XP_006506566
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MGI ID |
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MGI Symbol |
Zfp422
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OMIM |
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CCDS |
CCDS20459
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HPRD |
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IMGT |
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EMBL |
AF281634
AK082970
AK169251
BC018339
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GenPept |
AAG12466
AAH18339
BAC38716
BAE41015
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