Version 5.4
Mus musculus Protein: Abtb1
Summary
InnateDB Protein IDBP-167317.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Abtb1
Protein Name ankyrin repeat and BTB (POZ) domain containing 1
Synonyms AI847549; BC003234; BPOZ; EF1ABP;
Species Mus musculus
Ensembl Protein ENSMUSP00000032169
InnateDB Gene IDBG-167315 (Abtb1)
Protein Structure
UniProt Annotation
Function May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes (By similarity). {ECO:0000250UniProtKB:Q969K4}.
Subcellular Localization Cytoplasm {ECO:0000250UniProtKB:Q969K4}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003746 translation elongation factor activity
GO:0005515 protein binding
Biological Process
GO:0006414 translational elongation
GO:0008150 biological_process
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:1933148
InterPro IPR000210 BTB/POZ-like
IPR002110 Ankyrin repeat
IPR011333 BTB/POZ fold
IPR013069 BTB/POZ
IPR020683 Ankyrin repeat-containing domain
PFAM PF00023
PF13606
PF00651
PF11929
PF12796
PRINTS PR01415
PIRSF
SMART SM00225
SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99LJ2
PhosphoSite PhosphoSite-Q99LJ2
TrEMBL
UniProt Splice Variant
Entrez Gene 80283
UniGene Mm.399629
RefSeq NP_084527
MGI ID
MGI Symbol Abtb1
OMIM
CCDS CCDS20339
HPRD
IMGT
EMBL AB053477 AK088437 BC003234
GenPept AAH03234 BAB55652 BAC40352

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca