Mus musculus Protein: Sdha
Summary
InnateDB Protein IDBP-167331.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sdha
Protein Name succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
Synonyms 1500032O14Rik; 2310034D06Rik; 4921513A11; C81073; FP; SDH2; SDHF;
Species Mus musculus
Ensembl Protein ENSMUSP00000022062
InnateDB Gene IDBG-167329 (Sdha)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 60 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 60 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000104 succinate dehydrogenase activity
GO:0005515 protein binding
GO:0008177 succinate dehydrogenase (ubiquinone) activity
GO:0016491 oxidoreductase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0050660 flavin adenine dinucleotide binding
Biological Process
GO:0006099 tricarboxylic acid cycle
GO:0006105 succinate metabolic process
GO:0007399 nervous system development
GO:0022900 electron transport chain
GO:0022904 respiratory electron transport chain
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005749 mitochondrial respiratory chain complex II
Protein Structure and Domains
PDB ID MGI:1914195
InterPro IPR003953 FAD binding domain
IPR011281 Succinate dehydrogenase, flavoprotein subunit
IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit
IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal
IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
PFAM PF00890
PF02910
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8K2B3
PhosphoSite PhosphoSite-Q8K2B3
TrEMBL Q6IWE1
UniProt Splice Variant
Entrez Gene 66945
UniGene Mm.158231
RefSeq NP_075770
MGI ID
MGI Symbol Sdha
OMIM
CCDS CCDS26643
HPRD
IMGT
EMBL AF095938 AK004362 AK029520 AK034928 AK049590 AK050475 AK075990 AK145923 AK147286 AK147624 AK153085 AK162148 AK169254 AY618570 BC011301 BC031849 DQ402975
GenPept AAC72373 AAH11301 AAH31849 AAT40731 ABD77308 BAC26491 BAC28884 BAC33831 BAC34276 BAC36101 BAE26754 BAE27822 BAE28032 BAE31710 BAE36754 BAE41018 BAE43173