Version 5.4
Mus musculus Protein: Fam32a
Summary
InnateDB Protein IDBP-167689.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fam32a
Protein Name family with sequence similarity 32, member A
Synonyms 2510049I19Rik; AW822030; OTAG-12; Otag12;
Species Mus musculus
Ensembl Protein ENSMUSP00000003123
InnateDB Gene IDBG-167687 (Fam32a)
Protein Structure
UniProt Annotation
Function May induce G2 arrest and apoptosis (By similarity). May also increase cell sensitivity to apoptotic stimuli (By similarity). In cell lines, may play a role in the inhibition of anchor-independent cell growth. {ECO:0000250, ECO:0000269PubMed:21339736}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity Widely expressed, with highest level in pancreas and lowest in muscle. {ECO:0000269PubMed:21339736}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006915 apoptotic process
GO:0007049 cell cycle
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID MGI:1915172
InterPro IPR013865 Protein of unknown function DUF1754, eukaryotic
PFAM PF08555
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CR80
PhosphoSite PhosphoSite-Q9CR80
TrEMBL
UniProt Splice Variant
Entrez Gene 67922
UniGene Mm.391921
RefSeq NP_080731
MGI ID
MGI Symbol Fam32a
OMIM
CCDS CCDS52595
HPRD
IMGT
EMBL AB041658 AK008285 AK011922 AK075976 AK082792 AK150416 BC006058
GenPept AAH06058 BAB25576 BAB27918 BAB93548 BAC36089 BAC38622 BAE29540

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca