InnateDB Protein
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IDBP-167792.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Poldip3
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Protein Name
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polymerase (DNA-directed), delta interacting protein 3
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Synonyms
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1110008P04Rik; AA408269; AL022852; C77954; mKIAA1649; PDIP46; SKAR;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000054548
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InnateDB Gene
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IDBG-167790 (Poldip3)
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Protein Structure
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Function |
Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by assoociation with the TREX complex (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000250}. Nucleus speckle {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Nucleocytoplasmic shuttling protein. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated |
Total |
8
[view]
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Protein-Protein |
8
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
15 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1921076
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InterPro |
IPR000504
RNA recognition motif domain
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PFAM |
PF00076
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PRINTS |
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PIRSF |
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SMART |
SM00360
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TIGRFAMs |
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Modification |
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SwissProt |
Q8BG81
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PhosphoSite |
PhosphoSite-Q8BG81
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TrEMBL |
Q571G8
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UniProt Splice Variant |
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Entrez Gene |
73826
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UniGene |
Mm.406268
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RefSeq |
NP_848742
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MGI ID |
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MGI Symbol |
Poldip3
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OMIM |
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CCDS |
CCDS27697
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HPRD |
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IMGT |
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EMBL |
AK081139
AK083924
AK087446
AK220221
AL591952
BC037652
BC046505
BC058225
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GenPept |
AAH37652
AAH46505
AAH58225
BAC38144
BAC39068
BAC39877
BAD90146
CAQ51827
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