Version 5.4
Mus musculus Protein: Insl5
Summary
InnateDB Protein IDBP-168601.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Insl5
Protein Name insulin-like 5
Synonyms RIF2;
Species Mus musculus
Ensembl Protein ENSMUSP00000081416
InnateDB Gene IDBG-168599 (Insl5)
Protein Structure
UniProt Annotation
Function May have a role in gut contractility or in thymic development and regulation. Activates RXFP4 with high potency and appears to be the endogenous ligand for this receptor (By similarity). {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000250}.
Disease Associations
Tissue Specificity Highest expression in colon with lower levels in thymus. Minimal levels in testis. {ECO:0000269PubMed:10458910}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
Biological Process
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:1346085
InterPro IPR016179 Insulin-like
PFAM PF00049
PRINTS
PIRSF
SMART SM00078
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9WUG6
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 23919
UniGene Mm.100163
RefSeq NP_035961
MGI ID
MGI Symbol Insl5
OMIM
CCDS CCDS18406
HPRD
IMGT
EMBL AF054842 AF054843 AF076971 AF133817 BC010968
GenPept AAD29687 AAD48089 AAF09093 AAF09094 AAH10968

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca