Mus musculus Protein: Wnt10a
Summary
InnateDB Protein IDBP-168780.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wnt10a
Protein Name wingless related MMTV integration site 10a
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000006718
InnateDB Gene IDBG-168778 (Wnt10a)
Protein Structure
UniProt Annotation
Function Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters.
Subcellular Localization Secreted, extracellular space, extracellular matrix.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005109 frizzled binding
Biological Process
GO:0001942 hair follicle development
GO:0007165 signal transduction
GO:0007267 cell-cell signaling
GO:0007275 multicellular organismal development
GO:0009887 organ morphogenesis
GO:0010628 positive regulation of gene expression
GO:0014033 neural crest cell differentiation
GO:0016055 Wnt signaling pathway
GO:0030182 neuron differentiation
GO:0031069 hair follicle morphogenesis
GO:0042476 odontogenesis
GO:0042487 regulation of odontogenesis of dentin-containing tooth
GO:0043586 tongue development
GO:0043588 skin development
GO:0045165 cell fate commitment
GO:0048730 epidermis morphogenesis
GO:0048733 sebaceous gland development
GO:0071560 cellular response to transforming growth factor beta stimulus
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID MGI:108071
InterPro IPR005817 Wnt
IPR013302 Wnt-10 protein
PFAM PF00110
PRINTS PR01349
PR01893
PIRSF
SMART SM00097
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P70701
PhosphoSite PhosphoSite-P70701
TrEMBL
UniProt Splice Variant
Entrez Gene 22409
UniGene Mm.5130
RefSeq NP_033544
MGI ID
MGI Symbol Wnt10a
OMIM
CCDS CCDS15057
HPRD
IMGT
EMBL BC014737 U61969
GenPept AAB08085 AAH14737