InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Imp3

Summary

InnateDB Protein

IDBP-169002.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Imp3

Protein Name

IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)

Synonyms

1190002L16Rik; AI256594;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000034827

InnateDB Gene

IDBG-169000 (Imp3)

Protein Structure

UniProt Annotation

Function

Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus, nucleolus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0019843	rRNA binding
GO:0030519	snoRNP binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006364

rRNA processing

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0030529	ribonucleoprotein complex

Protein Structure and Domains

PDB ID

MGI:1916119

InterPro

IPR001912 Ribosomal protein S4/S9, N-terminal
IPR002942 RNA-binding S4 domain

PFAM

PF00163
PF01479

PRINTS

PIRSF

SMART

SM00363

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q921Y2

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

102462

UniGene

Mm.410018

RefSeq

NP_598737

MGI ID

MGI Symbol

Imp3

OMIM

CCDS

CCDS23213

HPRD

IMGT

EMBL

BC009145

GenPept

AAH09145