Mus musculus Protein: Wnt8b
Summary
InnateDB Protein IDBP-169883.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wnt8b
Protein Name wingless related MMTV integration site 8b
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000042867
InnateDB Gene IDBG-169881 (Wnt8b)
Protein Structure
UniProt Annotation
Function Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus.
Subcellular Localization Secreted, extracellular space, extracellular matrix.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005109 frizzled binding
Biological Process
GO:0007165 signal transduction
GO:0007267 cell-cell signaling
GO:0007275 multicellular organismal development
GO:0009887 organ morphogenesis
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0016055 Wnt signaling pathway
GO:0030182 neuron differentiation
GO:0045165 cell fate commitment
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID MGI:109485
InterPro IPR005817 Wnt
IPR013301 Wnt-8 protein
PFAM PF00110
PRINTS PR01349
PR01892
PIRSF
SMART SM00097
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9WUD6
PhosphoSite PhosphoSite-
TrEMBL Q8BQD1
UniProt Splice Variant
Entrez Gene 22423
UniGene Mm.88365
RefSeq NP_035850
MGI ID
MGI Symbol Wnt8b
OMIM
CCDS CCDS50446
HPRD
IMGT
EMBL AC151478 AF130349 AK050992
GenPept AAD31816 BAC34490