InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cox5a

Summary

InnateDB Protein

IDBP-170227.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cox5a

Protein Name

cytochrome c oxidase, subunit Va

Synonyms

AA959768; CcOX;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000000090

InnateDB Gene

IDBG-170225 (Cox5a)

Protein Structure

UniProt Annotation

Function

This is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Subcellular Localization

Mitochondrion inner membrane.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	12 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004129	cytochrome-c oxidase activity
GO:0046872	metal ion binding

Biological Process

GO:1902600

hydrogen ion transmembrane transport

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:88474

InterPro

IPR003204 Cytochrome c oxidase, subunit Va/VI

PFAM

PF02284

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P12787

PhosphoSite

PhosphoSite-P12787

TrEMBL

UniProt Splice Variant

Entrez Gene

12858

UniGene

Mm.398320

RefSeq

NP_031773

MGI ID

MGI Symbol

Cox5a

OMIM

CCDS

CCDS23223

HPRD

IMGT

EMBL

AK018723 BC034302 X15963

GenPept

AAH34302 BAB31369 CAA34085