Version 5.4
Mus musculus Protein: Shisa2
Summary
InnateDB Protein IDBP-170235.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Shisa2
Protein Name shisa homolog 2 (Xenopus laevis)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000059391
InnateDB Gene IDBG-170233 (Shisa2)
Protein Structure
UniProt Annotation
Function Plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling. {ECO:0000269PubMed:16773659, ECO:0000269PubMed:17481602}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007275 multicellular organismal development
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2444716
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8QZV2
PhosphoSite PhosphoSite-Q8QZV2
TrEMBL
UniProt Splice Variant
Entrez Gene 219134
UniGene Mm.394401
RefSeq NP_663438
MGI ID
MGI Symbol Shisa2
OMIM
CCDS CCDS27173
HPRD
IMGT
EMBL AB280737 AK034905 AK087512 BC024118 BC057640 DQ342342
GenPept AAH24118 AAH57640 ABC69144 BAC28876 BAC39906 BAF57482

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca