InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lsm3

Summary

InnateDB Protein

IDBP-170362.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lsm3

Protein Name

LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)

Synonyms

1010001J12Rik; 2610005D18Rik; 6030401D18Rik; SMX4; USS2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000044178

InnateDB Gene

IDBG-170360 (Lsm3)

Protein Structure

UniProt Annotation

Function

Binds specifically to the 3'-terminal U-tract of U6 snRNA. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	5 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	31 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0030629	U6 snRNA 3'-end binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000398	mRNA splicing, via spliceosome
GO:0006397	mRNA processing
GO:0008380	RNA splicing

Cellular Component

GO:0005634	nucleus
GO:0005681	spliceosomal complex
GO:0030529	ribonucleoprotein complex
GO:0046540	U4/U6 x U5 tri-snRNP complex
GO:0071013	catalytic step 2 spliceosome