Version 5.4
Mus musculus Protein: Tuft1
Summary
InnateDB Protein IDBP-170507.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tuft1
Protein Name tuftelin 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000006123
InnateDB Gene IDBG-170505 (Tuft1)
Protein Structure
UniProt Annotation
Function Involved in the mineralization and structural organization of enamel.
Subcellular Localization Secreted {ECO:0000250}. Note=Secreted at a very early stage of enamel formation, concentrated at the dentin- enamel junction and tightly bound to the surface of the growing crystallites. {ECO:0000250}.
Disease Associations
Tissue Specificity Ameloblasts, and also non-odontogenic tissues including kidney, lung, liver and testis. {ECO:0000269PubMed:9839784}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0031214 biomineral tissue development
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:109572
InterPro IPR009053 Prefoldin
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O08970
PhosphoSite PhosphoSite-
TrEMBL Q3V1F5
UniProt Splice Variant
Entrez Gene 22156
UniGene Mm.488137
RefSeq NP_035786
MGI ID
MGI Symbol Tuft1
OMIM
CCDS CCDS17595
HPRD
IMGT
EMBL AF002860 AF047704 AK132488 BC019213
GenPept AAB60891 AAC04577 AAH19213 BAE21196

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca