InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sfxn3

Summary

InnateDB Protein

IDBP-170523.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sfxn3

Protein Name

sideroflexin 3

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000059419

InnateDB Gene

IDBG-170521 (Sfxn3)

Protein Structure

UniProt Annotation

Function

Potential iron transporter.

Subcellular Localization

Mitochondrion membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Widely expressed. {ECO:0000269PubMed:11274051}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0008324	cation transmembrane transporter activity

Biological Process

GO:0006812	cation transport
GO:0008150	biological_process
GO:0055072	iron ion homeostasis
GO:0055085	transmembrane transport

Cellular Component

GO:0005739	mitochondrion
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0031966	mitochondrial membrane

Protein Structure and Domains

PDB ID

MGI:2137679

InterPro

IPR004686 Tricarboxylate/iron carrier

PFAM

PF03820

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q91V61

PhosphoSite

PhosphoSite-Q91V61

TrEMBL

UniProt Splice Variant

Entrez Gene

94280

UniGene

Mm.454959

RefSeq

NP_444427

MGI ID

MGI Symbol

Sfxn3

OMIM

CCDS

CCDS29856

HPRD

IMGT

EMBL

AF325262 AK034514 AK089985 BC012208

GenPept

AAH12208 AAK39430 BAC28739 BAC41029