Version 5.4
Mus musculus Protein: Gmppa
Summary
InnateDB Protein IDBP-171200.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gmppa
Protein Name GDP-mannose pyrophosphorylase A
Synonyms 1810012N01Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000035564
InnateDB Gene IDBG-171196 (Gmppa)
Protein Structure
UniProt Annotation
Function May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity Widely expressed. {ECO:0000269PubMed:24035193}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0009058 biosynthetic process
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1916330
InterPro IPR001451 Bacterial transferase hexapeptide repeat
IPR005835 Nucleotidyl transferase
IPR029044 Nucleotide-diphospho-sugar transferases
PFAM PF00132
PF00483
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q922H4
PhosphoSite PhosphoSite-Q922H4
TrEMBL D3Z5Z5
UniProt Splice Variant
Entrez Gene 69080
UniGene Mm.490291
RefSeq NP_598469
MGI ID
MGI Symbol Gmppa
OMIM
CCDS CCDS15072
HPRD
IMGT
EMBL AC114651 AK150473 BC008116
GenPept AAH08116 BAE29590

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca