InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Uqcrq

Summary

InnateDB Protein

IDBP-171652.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Uqcrq

Protein Name

ubiquinol-cytochrome c reductase, complex III subunit VII

Synonyms

1100001F06Rik; 1500040F11Rik; 5830407L17Rik; 9.5kDa; AA959903; c1502; QP-C; Qpc; Uqcrb;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000053145

InnateDB Gene

IDBG-171650 (Uqcrq)

Protein Structure

UniProt Annotation

Function

This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit, together with cytochrome b, binds to ubiquinone.

Subcellular Localization

Mitochondrion inner membrane.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0008121	ubiquinol-cytochrome-c reductase activity

Biological Process

GO:0008150	biological_process
GO:0021539	subthalamus development
GO:0021548	pons development
GO:0021680	cerebellar Purkinje cell layer development
GO:0021766	hippocampus development
GO:0021794	thalamus development
GO:0021854	hypothalamus development
GO:0021860	pyramidal neuron development
GO:0030901	midbrain development
GO:0055114	oxidation-reduction process
GO:1902600	hydrogen ion transmembrane transport

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0070469	respiratory chain

Protein Structure and Domains

PDB ID

MGI:107807

InterPro

IPR004205 Cytochrome b-c1 complex subunit 8

PFAM

PF02939

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9CQ69

PhosphoSite

PhosphoSite-Q9CQ69

TrEMBL

UniProt Splice Variant

Entrez Gene

22272

UniGene

Mm.467798

RefSeq

MGI ID

MGI Symbol

Uqcrq

OMIM

CCDS

CCDS36151

HPRD

IMGT

EMBL

AK002389 AK003160 AK005374 AK007982 BC028519

GenPept

AAH28519 BAB22063 BAB22613 BAB23983 BAB25388