Version 5.4
Mus musculus Protein: Cytip
Summary
InnateDB Protein IDBP-171960.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cytip
Protein Name cytohesin 1 interacting protein
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000028175
InnateDB Gene IDBG-171958 (Cytip)
Protein Structure
UniProt Annotation
Function By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Early endosome {ECO:0000250}. Note=Recruited from the cytosol to endosomes by SNX27. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0030155 regulation of cell adhesion
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005938 cell cortex
Protein Structure and Domains
PDB ID MGI:2183535
InterPro IPR001478 PDZ domain
PFAM PF00595
PF13180
PRINTS
PIRSF
SMART SM00228
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91VY6
PhosphoSite PhosphoSite-Q91VY6
TrEMBL Q3THB7
UniProt Splice Variant
Entrez Gene 227929
UniGene Mm.489718
RefSeq NP_631939
MGI ID
MGI Symbol Cytip
OMIM
CCDS CCDS16048
HPRD
IMGT
EMBL AF192525 AF374273 AK089364 AK152784 AK157859 AK168343 AK169575 AK170544 AK171467 AK172071 AL928564 BC007144
GenPept AAF04842 AAH07144 AAL87039 BAC40855 BAE31493 BAE34237 BAE40280 BAE41236 BAE41869 BAE42473 BAE42810 CAM18785

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca