Version 5.4
Mus musculus Protein: Serinc5
Summary
InnateDB Protein IDBP-172267.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Serinc5
Protein Name serine incorporator 5
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000047547
InnateDB Gene IDBG-172265 (Serinc5)
Protein Structure
UniProt Annotation
Function Enhances the incorporation of serine into phosphatidylserine and sphingolipids. May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes (By similarity). {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006658 phosphatidylserine metabolic process
GO:0008654 phospholipid biosynthetic process
GO:0042552 myelination
GO:0051347 positive regulation of transferase activity
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043209 myelin sheath
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:2444223
InterPro IPR005016 TMS membrane protein/tumour differentially expressed protein
PFAM PF03348
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BHJ6
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 218442
UniGene Mm.472145
RefSeq NP_766176
MGI ID
MGI Symbol Serinc5
OMIM
CCDS CCDS36744
HPRD
IMGT
EMBL AB029501 AK037699 AK054475 AK136799 AK165334 BC049189 BC062131
GenPept AAH49189 AAH62131 BAC29851 BAC35794 BAC44829 BAE23132 BAE38139

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca