InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Podn

Summary

InnateDB Protein

IDBP-172324.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Podn

Protein Name

podocan

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000048962

InnateDB Gene

IDBG-172320 (Podn)

Protein Structure

UniProt Annotation

Function

Negatively regulates cell proliferation and cell migration, especially in smooth muscle cells. {ECO:0000250}.

Subcellular Localization

Secreted, extracellular space, extracellular matrix {ECO:0000269PubMed:12796502}.

Disease Associations

Tissue Specificity

Kidney. Expressed in podocytes and likely vascular endothelial cells within the glomerulus. {ECO:0000269PubMed:12796502}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005518	collagen binding

Biological Process

GO:0008285	negative regulation of cell proliferation
GO:0030336	negative regulation of cell migration

Cellular Component

GO:0005578	proteinaceous extracellular matrix
GO:0005615	extracellular space
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:2674939

InterPro

IPR000372 Leucine-rich repeat-containing N-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype

PFAM

PF01462
PF00560
PF13504
PF13855

PRINTS

PIRSF

SMART

SM00013
SM00369

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q7TQ62

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

242608

UniGene

Mm.74710

RefSeq

XP_006503155

MGI ID

MGI Symbol

Podn

OMIM

CCDS

CCDS18445

HPRD

IMGT

EMBL

AK034987 AL611936 AY313606 BC094340 CH466527

GenPept

AAH94340 AAP79897 BAC28904 CAM23596 EDL30756 EDL30757