InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Neil2

Summary

InnateDB Protein

IDBP-172421.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Neil2

Protein Name

nei like 2 (E. coli)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000045200

InnateDB Gene

IDBG-172419 (Neil2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003684	damaged DNA binding
GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity
GO:0008017	microtubule binding
GO:0008270	zinc ion binding
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds

Biological Process

GO:0000737	DNA catabolic process, endonucleolytic
GO:0006281	DNA repair
GO:0006284	base-excision repair
GO:0006289	nucleotide-excision repair

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005876	spindle microtubule
GO:0015630	microtubule cytoskeleton

Protein Structure and Domains

PDB ID

MGI:2686058

InterPro

IPR000214 Zinc finger, DNA glycosylase/AP lyase-type
IPR010979 Ribosomal protein S13-like, H2TH
IPR012319 DNA glycosylase/AP lyase, catalytic domain
IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding

PFAM

PF01149
PF06831

PRINTS

PIRSF

SMART

SM00898

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q6R2P8