InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ncam2

Summary

InnateDB Protein

IDBP-172514.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ncam2

Protein Name

neural cell adhesion molecule 2

Synonyms

Ncam-2; Ocam; RNCAM;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000063468

InnateDB Gene

IDBG-172510 (Ncam2)

Protein Structure

UniProt Annotation

Function

May play important roles in selective fasciculation and zone-to-zone projection of the primary olfactory axons.

Subcellular Localization

Isoform Long: Cell membrane; Single-pass type I membrane protein.Isoform Short: Cell membrane; Lipid-anchor, GPI-anchor.

Disease Associations

Tissue Specificity

Expressed in subsets of both olfactory and vomeronasal neurons in a zone-specific manner.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0007155	cell adhesion
GO:0007413	axonal fasciculation
GO:0007608	sensory perception of smell

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0030424	axon
GO:0031225	anchored component of membrane

Protein Structure and Domains

PDB ID

MGI:97282

InterPro

IPR003596 Immunoglobulin V-set, subgroup
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR009138 Neural cell adhesion
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin

PFAM

PF00041
PF01108
PF07679
PF07686
PF00047

PRINTS

PR01838

PIRSF

SMART

SM00406
SM00408
SM00409
SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt