InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tmem165

Summary

InnateDB Protein

IDBP-172798.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tmem165

Protein Name

transmembrane protein 165

Synonyms

AV026557; pFT27; Tpardl; Tparl;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000031144

InnateDB Gene

IDBG-172796 (Tmem165)

Protein Structure

UniProt Annotation

Function

May function as a calcium/proton transporter involved in calcium and in lysosomal pH homeostasis. Therefore, it may play an indirect role in protein glycosylation (By similarity). {ECO:0000250}.

Subcellular Localization

Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Golgi apparatus, trans- Golgi network membrane {ECO:0000250}. Lysosome membrane {ECO:0000250}. Early endosome membrane {ECO:0000250}. Late endosome membrane {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0006487	protein N-linked glycosylation
GO:0006874	cellular calcium ion homeostasis
GO:0032472	Golgi calcium ion transport
GO:0035751	regulation of lysosomal lumen pH

Cellular Component

GO:0000139	Golgi membrane
GO:0005765	lysosomal membrane
GO:0005794	Golgi apparatus
GO:0010008	endosome membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0031901	early endosome membrane
GO:0031902	late endosome membrane
GO:0032588	trans-Golgi network membrane
GO:0043231	intracellular membrane-bounded organelle