InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Scg2

Summary

InnateDB Protein

IDBP-172844.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Scg2

Protein Name

secretogranin II

Synonyms

Chgc; SgII;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000062556

InnateDB Gene

IDBG-172842 (Scg2)

Protein Structure

UniProt Annotation

Function

Secretogranin-2 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.

Subcellular Localization

Secreted. Note=Neuroendocrine and endocrine secretory granules.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005125	cytokine activity
GO:0042056	chemoattractant activity

Biological Process

GO:0000165	MAPK cascade
GO:0001525	angiogenesis
GO:0001938	positive regulation of endothelial cell proliferation
GO:0006928	cellular component movement
GO:0035556	intracellular signal transduction
GO:0048245	eosinophil chemotaxis
GO:0050918	positive chemotaxis
GO:0050930	induction of positive chemotaxis
GO:2000352	negative regulation of endothelial cell apoptotic process
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway