InnateDB Protein
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IDBP-173388.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Rfx1
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Protein Name
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regulatory factor X, 1 (influences HLA class II expression)
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Synonyms
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AI047719; AI385641;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000005600
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InnateDB Gene
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IDBG-173386 (Rfx1)
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Protein Structure
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|
Function |
Regulatory factor essential for MHC class II genes expression. Binds to the X boxes of MHC class II genes (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000255PROSITE- ProRule:PRU00858}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
|
Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
12 [view]
|
|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:105982
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InterPro |
IPR003150
DNA-binding RFX-type winged-helix domain
IPR007668
RFX1 transcription activation region
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PFAM |
PF02257
PF04589
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P48377
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PhosphoSite |
PhosphoSite-P48377
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TrEMBL |
Q8BYY2
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UniProt Splice Variant |
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Entrez Gene |
19724
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UniGene |
Mm.7892
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RefSeq |
NP_033081
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MGI ID |
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MGI Symbol |
Rfx1
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OMIM |
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CCDS |
CCDS22468
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HPRD |
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IMGT |
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EMBL |
AK037226
BC057018
CH466525
X76088
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GenPept |
AAH57018
BAC29765
CAA53702
EDL10930
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