InnateDB Protein
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IDBP-173618.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Cnnm2
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Protein Name
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cyclin M2
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Synonyms
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Acdp2; AU015877; AW048635; Clp2;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000076850
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InnateDB Gene
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IDBG-173616 (Cnnm2)
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Protein Structure
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Function |
Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+). {ECO:0000269PubMed:15899945}.
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Subcellular Localization |
Cell membrane {ECO:0000269PubMed:22399287}; Multi-pass membrane protein {ECO:0000269PubMed:22399287}.
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Disease Associations |
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Tissue Specificity |
Widely expressed, with highest levels in kidney, lung, spleen and testis. In the kidney, predominantly expressed in the distal convoluted tubule and, at lower levels, in the connecting tubule (at protein level). {ECO:0000269PubMed:14723793, ECO:0000269PubMed:15899945, ECO:0000269PubMed:22399287}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2151054
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InterPro |
IPR002550
Domain of unknown function DUF21
IPR018490
Cyclic nucleotide-binding-like
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PFAM |
PF01595
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q3TWN3
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PhosphoSite |
PhosphoSite-Q3TWN3
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
94219
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UniGene |
Mm.418583
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RefSeq |
NP_001095941
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MGI ID |
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MGI Symbol |
Cnnm2
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OMIM |
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CCDS |
CCDS50460
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HPRD |
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IMGT |
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EMBL |
AC122442
AC161865
AF216961
AK044400
AK159616
BC027387
BC052513
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GenPept |
AAF86373
AAH27387
AAH52513
BAC31904
BAE35233
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