InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Srp72

Summary

InnateDB Protein

IDBP-173760.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Srp72

Protein Name

signal recognition particle 72

Synonyms

5730576P14Rik; 72kDa; AI132477; BC019196; C77589;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000098648

InnateDB Gene

IDBG-173756 (Srp72)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005047	signal recognition particle binding
GO:0005515	protein binding
GO:0008312	7S RNA binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0042493	response to drug

Cellular Component

GO:0005730	nucleolus
GO:0005783	endoplasmic reticulum
GO:0005786	signal recognition particle, endoplasmic reticulum targeting
GO:0005886	plasma membrane
GO:0048500	signal recognition particle

Protein Structure and Domains

PDB ID

MGI:1333795

InterPro

IPR013026 Tetratricopeptide repeat-containing domain
IPR013699 Signal recognition particle, SRP72 subunit, RNA-binding
IPR019734 Tetratricopeptide repeat

PFAM

PF08492
PF13174
PF13176
PF13181

PRINTS

PIRSF

SMART

SM00028

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite