InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ina

Summary

InnateDB Protein

IDBP-173829.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ina

Protein Name

internexin neuronal intermediate filament protein, alpha

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000041347

InnateDB Gene

IDBG-173827 (Ina)

Protein Structure

UniProt Annotation

Function

Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005198	structural molecule activity
GO:0005515	protein binding

Biological Process

GO:0007399	nervous system development
GO:0021762	substantia nigra development
GO:0030154	cell differentiation
GO:0045104	intermediate filament cytoskeleton organization
GO:0060052	neurofilament cytoskeleton organization