Version 5.4
Homo sapiens Protein: SHISA2
Summary
InnateDB Protein IDBP-17388.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SHISA2
Protein Name shisa homolog 2 (Xenopus laevis)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000313079
InnateDB Gene IDBG-17386 (SHISA2)
Protein Structure
UniProt Annotation
Function Plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling. {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007275 multicellular organismal development
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6UWI4
PhosphoSite PhosphoSite-Q6UWI4
TrEMBL
UniProt Splice Variant
Entrez Gene 387914
UniGene Hs.619232
RefSeq NP_001007539
HUGO HGNC:20366
OMIM
CCDS CCDS31951
HPRD 16589
IMGT
EMBL AL139004 AY358775 BC132898 BC137092 CH471075
GenPept AAI32899 AAI37093 AAQ89135 CAH73406 EAX08378

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca