InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc7a9

Summary

InnateDB Protein

IDBP-174333.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc7a9

Protein Name

solute carrier family 7 (cationic amino acid transporter, y+ system), member 9

Synonyms

CSNU3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000032703

InnateDB Gene

IDBG-174331 (Slc7a9)

Protein Structure

UniProt Annotation

Function

Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). Thought to be responsible for the high- affinity reabsorption of cystine in the kidney proximal tubule.

Subcellular Localization

Cell membrane {ECO:0000269PubMed:12167606}; Multi-pass membrane protein {ECO:0000269PubMed:12167606}.

Disease Associations

Tissue Specificity

Expressed in the brush border membrane in the kidney (at protein level). {ECO:0000269PubMed:12167606}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0015171	amino acid transmembrane transporter activity
GO:0015175	neutral amino acid transmembrane transporter activity
GO:0042605	peptide antigen binding

Biological Process

GO:0003333	amino acid transmembrane transport
GO:0006810	transport
GO:0006865	amino acid transport
GO:0015804	neutral amino acid transport
GO:0055085	transmembrane transport