Version 5.4
Mus musculus Protein: Mis18a
Summary
InnateDB Protein IDBP-174873.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mis18a
Protein Name RIKEN cDNA 2610039C10 gene
Synonyms 2610039C10Rik; 2810018N07Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000097150
InnateDB Gene IDBG-174869 (Mis18a)
Protein Structure
UniProt Annotation
Function Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Chromosome, centromere {ECO:0000250}. Note=Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007059 chromosome segregation
GO:0007067 mitotic nuclear division
GO:0034080 centromere-specific nucleosome assembly
GO:0044030 regulation of DNA methylation
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1913828
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CZJ6
PhosphoSite PhosphoSite-Q9CZJ6
TrEMBL
UniProt Splice Variant
Entrez Gene 66578
UniGene Mm.392808
RefSeq NP_079918
MGI ID
MGI Symbol Mis18a
OMIM
CCDS CCDS28316
HPRD
IMGT
EMBL AK012533 AK163310 BC079900
GenPept AAH79900 BAB28302 BAE37292

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca