InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Farsa

Summary

InnateDB Protein

IDBP-175013.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Farsa

Protein Name

phenylalanyl-tRNA synthetase, alpha subunit

Synonyms

0610012A19Rik; Farsla;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000003906

InnateDB Gene

IDBG-175011 (Farsa)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Experimentally validated
Total	14 [view]
Protein-Protein	13 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000049	tRNA binding
GO:0000166	nucleotide binding
GO:0004812	aminoacyl-tRNA ligase activity
GO:0004826	phenylalanine-tRNA ligase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006418	tRNA aminoacylation for protein translation
GO:0006432	phenylalanyl-tRNA aminoacylation
GO:0008150	biological_process
GO:0043039	tRNA aminoacylation

Cellular Component

GO:0005737	cytoplasm
GO:0016020	membrane

Protein Structure and Domains

PDB ID

MGI:1913840

InterPro

IPR002314 Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain
IPR002319 Phenylalanyl-tRNA synthetase
IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N)
IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit
IPR006195 Aminoacyl-tRNA synthetase, class II
IPR013196 Helix-turn-helix, type 11

PFAM

PF00587
PF01409
PF00152
PF08279

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8C0C7

PhosphoSite