InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: COQ7

Summary

InnateDB Protein

IDBP-17530.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

COQ7

Protein Name

coenzyme Q7 homolog, ubiquinone (yeast)

Synonyms

CAT5; CLK-1; CLK1;

Species

Homo sapiens

Ensembl Protein

ENSP00000322316

InnateDB Gene

IDBG-17528 (COQ7)

Protein Structure

UniProt Annotation

Function

Involved in lifespan determination in ubiquinone- independent manner. Involved in ubiquinone biosynthesis. Potential central metabolic regulator (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Note=Synthesized as a preprotein that is imported into the mitochondrial matrix, where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane. {ECO:0000250}.

Disease Associations

Tissue Specificity

Expressed dominantly in heart and skeletal muscle.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0046872	metal ion binding

Biological Process

GO:0001306	age-dependent response to oxidative stress
GO:0001701	in utero embryonic development
GO:0001841	neural tube formation
GO:0006744	ubiquinone biosynthetic process
GO:0006979	response to oxidative stress
GO:0008340	determination of adult lifespan
GO:0022008	neurogenesis
GO:0022904	respiratory electron transport chain
GO:0034599	cellular response to oxidative stress
GO:0042775	mitochondrial ATP synthesis coupled electron transport
GO:0044281	small molecule metabolic process
GO:0055114	oxidation-reduction process
GO:0070584	mitochondrion morphogenesis