Version 5.4
| Mus musculus Protein: Adam7 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-176567.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Adam7 | ||||||||
| Protein Name | a disintegrin and metallopeptidase domain 7 | ||||||||
| Synonyms | 9230104J12Rik; EAP1; EAPI; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000022640 | ||||||||
| InnateDB Gene | IDBG-176565 (Adam7) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein. | ||||||||
| Subcellular Localization | Membrane; Single-pass type I membrane protein. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Expressed in the apical region of the proximal caput epididymal epithelium and in the anterior pituitary, specifically, in the gonadotrophes. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:107247 | ||||||||
| InterPro |
IPR001590
Peptidase M12B, ADAM/reprolysin IPR001762 Blood coagulation inhibitor, Disintegrin IPR002870 Peptidase M12B, propeptide IPR006586 ADAM, cysteine-rich |
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| PFAM |
PF01421
PF00200 PF01562 PF08516 |
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| PRINTS |
PR00289
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| PIRSF | |||||||||
| SMART |
SM00050
SM00608 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | O35227 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | Q3TNV5 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 11500 | ||||||||
| UniGene | Mm.261495 | ||||||||
| RefSeq | NP_031428 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Adam7 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS27234 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AC154706 AF013107 AK164965 | ||||||||
| GenPept | AAC53368 BAE37982 | ||||||||