InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Itfg1

Summary

InnateDB Protein

IDBP-177424.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Itfg1

Protein Name

integrin alpha FG-GAP repeat containing 1

Synonyms

2310047C21Rik; AI314457; Cda08; D8Wsu49e;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000034140

InnateDB Gene

IDBG-177422 (Itfg1)

Protein Structure

UniProt Annotation

Function

Modulator of T-cell function. Has a protective effect in graft versus host disease model. {ECO:0000269PubMed:12598909}.

Subcellular Localization

Secreted {ECO:0000305}. Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0005575	cellular_component
GO:0005576	extracellular region
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:106419

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q99KW9

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

71927

UniGene

Mm.474325

RefSeq

NP_082283

MGI ID

MGI Symbol

Itfg1

OMIM

CCDS

CCDS40424

HPRD

IMGT

EMBL

AC117185 AC158357 AK009867 BC003977

GenPept

AAH03977 BAB26552